Wpływ wybranych preparatów fluorowych na mikrostrukturę szkliwa z wczesnymi zmianami próchnicowymi

*Agnieszka Mielczarek¹, Joanna Michalik², Marek Kujawa³

Summary
Aim: The evaluation of the effect of selected fluoride formulations on microstructure of early caries lesions.
Material and methods: 120 polished human enamel specimens, embedded in cylindrical acrylic blocks served as a study material. The specimens were randomly assigned to 4 equinumerous groups, according to baseline microhardness of the enamel surface. The enamel samples were subjected to the preliminary demineralization, simulating the initial carious lesion. Upon demineralization one half of each specimen was covered with a protective varnish. Specimens were subjected to the 3 week cycle of pH changes, according to the protocol as follows: AC group – toothpaste containing nanohydroxyapatite (nano-HAP) and 1450 ppm F b.i.d., D group – Duraphat varnish once a week and toothpaste containing 1450 ppm b.i.d., F group – toothpaste containing 1450 ppm b.i.d., K(-) group – distilled water application. Samples were sectioned longitudinally and obtained surfaces were prepared for SEM examination.
Results: The analysis of SEM images revealed that toothpaste containing nano-HAP and fluoride was the most effective to reduce demineralization lesions within the subsurface enamel region, while Duraphat application was especially effective on the enamel surface.
Conclusions: The results proved that all the therapeutic protocols assessed succeeded to inhibit caries progression as well as to increase enamel mineralization. The effectiveness of particular remineralization procedures differed between various areas of carious lesions.

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