Wpływ kadmu i wysiłku fizycznego na wybrane markery w tkankach szczura.
III. N-acetyl- beta-D-glucozaminidaza (NAG EC 3.2.1.30)

Przemysław Nowak¹, Halina Milnerowicz², Krzysztof A. Sobiech³

Streszczenie

N-Acetyl-beta-D-glucosaminidase (NAG) apart from metallothioneine (MT) is considered to be a respected marker of toxic affecting of cadmium. The activity was determined using p-nitrophenyl-N-acetyl-beta-D-glucosaminide as a substrate. NAG activity was determined in homogenates of kidney, liver, pancreas, heart and skeletal muscles from rats chronicly intoxicated by cadmium acetate and physically efforted as it was described in the Part I. It was assumed, that the chronic cadmium exposure caused increase in the NAG activity in kidney, liver, heart and insignificant increase in the pancreas. The physical effort in rats evoked the NAG activity decrease in kidney, and it had none importance in other tissues.

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