Cystic fibrosis-related diabetes

© Borgis - New Medicine 1/2003, s. 8-11

Agnieszka Szypowska, Ewa Pańkowska

Summary
Cystic fibrosis-related diabetes has become increasingly common with the increased longevity of patients with cystic fibrosis. Identification of patients with abnormal glucose tolerance is important, because they are at greater risk of deterioration of lung function. Accelerated weight loss and deterioration of pulmonary function have been reported to occur up to 4 years before diabetes develops. They are also at risk for the development of microvascular complications. Diabetes might adversely affect cystic fibrosis morbidity and mortality rates and pulmonary function. The pathophysiology, clinical manifestation, diagnosis, and management of cystic fibrosis-related diabetes are reviewed.

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