Azithromycin vs. Clarithromycin and Co-amoxiclav: clinical and economic comparison in the treatment of acute otitis media in children

Henryk Kawalski, Ewa Blacha, Marek Kopacz, Mariusz Moś, Elżbieta Cierpioł-Tracz, Marek Wełniak, Beata Dudziak, Sonia Bojda, Bożena Kossowska, Ewa Gatniejewska, Michał Ligacz

Summary
170 children with acute otitis media were treated from 1999 to 2000. The patients were randomly divided into 3 groups. In particular groups therapy was performed with Azithromycin for 3 days, or with Co – amoxiclav and Clarithromycin for 10 days.
In the course of therapy bacteriological, biochemical, morphological and clinical parameters were examined. The results were analysed statistically and economically. A high efficiency was found for all antibiotics used. The best results were achieved with Azithromycin.

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