Platelets and Helicobacter pylori infection

Elzbieta Maciorkowska¹, Beata Szynaka², Maciej Kaczmarski¹, Andrzej Kemona²

Summary
The authors evaluated the ultrastructur of the gastric mucosa and fine blood vessels in two girls infected with H. pylori and peripheral blood thrombocytopaenia. Platelet-granulocyte or only platelet aggregates were found in the gastric mucosa of patients under the superficial epithelium in H. pylori accumulation sites, epithelial cell lesions and in the capillary lumen. Platelet aggregates adhered to basement membrane devoid of endothelial cells. Erythrocytes placed loosely or in agglomerations, eosinophil and neutrophil granulocytes, plasmocytes and mast cells were found beyond the vascular bed, most frequently close to vessels in damaged endothelium or with platelet aggregates.

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