Rola statyn, ze szczególnym uwzględnieniem simwastatyny, w farmakoterapii chorób układu krążenia

Krystyna Knypl

Summary
The role of statins, particularly simvastatin, in modern pharmacotherapy of cardiovascular diseases was presented. Since the results of a historical Scandinavian Simvastatin Survival Study (4S) were announced in 1994, statins have had a firm position both in primary and secondary prevention of coronary heart disease, myocardial infarction and stroke. High preventive effectiveness of simvastatin in 40 mg/day dose among high cardiovascular risk patients´ was revealed in Heart Protection Study in 2002.

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