Ocena skuteczności cetyryzyny i donosowej formy propionianu flutikazonu (Flixonase) w leczeniu przerostu trzeciego migdałka u dzieci uczulonych na roztocze kurzu domowego

Marek Modrzyński¹, Edward Zawisza², Janusz Królikiewicz⁵, Piotr Rapiejko³, Grzegorz Przybylski⁴

Summary
Allergic sensitisation of the airways occurs in the mucosa of the shock organ, or in the lymphatic stations draining these structures. The lymphatic structure closest to the nasal mucosa in humans is the adenoid.
Pediatric adenoidal obstruction of the nasal airway is associated with significant morbidity and is a frequent indication for surgery. Because efficacious medical alternatives to adenoidectomy are lacking, we assessed the potency of standard-dose topical nasal fluticasone propionate and cetirizine in reduction of adenoidal obstruction of the nasal airway. To examine the influence of these medicines on the adenoid hypertrophy (AH) we studied 43 children ages 4 to 9 years, who had AH and house dust mite allergy.
Properly administered aqueous nasal fluticasone propionate and cetirizine in standard doses can significantly reduce adenoidal hypertrophy and nasal airway obstructive symptoms in atopic children.

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