Primary woman neuroendocrine breast tumor – case report and review of the literature

*Konrad Wroński^{1, 2}, Maciej Żechowicz^{1, 3}, Leszek Frąckowiak^{1, 4}, Mariusz Koda⁵

Summary
Primary neuroendocrine breast carcinoma (NEBC) is extremely rare type of breast tumor and has been reported sporadically. Most neuroendocrine tumors are located in the gastrointestinal tract. This type of breast cancer was first time recognized by the WHO in 2003. Because of its rarity, there is little knowledge about its epidemiology, biology and there is no standard treatment protocol and a large variety of chemotherapy protocols have been employed in treating this disease.The primary neuroendocrine breast carcinomas may give distant metastasis to bone and liver but also to other sites include: lungs, mediastinal lymph nodes, adrenal glands, fallopian tubes, colon, ileum and pancreas. The treatment of neuroendorcine breast carcinomas need multimodal therapy. So that it is important to treat women in high specialized oncological centers.
The authors of this article presented a case of a 45-year-old Caucasian woman who was treated in the hospital because of primary neuroendocrine breast cancer. The authors performed a literature review on primary neuroendocrine breast cancer diagnosis and treatment.

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