Rośliny lecznicze z rodziny Dipsacaceae

Justyna Kukuła, *Ewa Witkowska-Banaszczak

Summary
Plants from the Dipsacaceae family have already been used in folk medicine since the Middle Ages, among other things, to treat diseases of the respiratory tract (for example, asthma, tuberculosis, pleurisy, cough), metabolic disorders (i.e. rheumatism, gout) as well as cutaneous conditions, such as ulcers or warts, as an agent with antiseptic properties and ones accelerating wound healing. They have also been used to fight toothache and rheumatic pain. They contain compounds from the groups of flavonoids, phenolic acids, triterpene saponosides and mono-, bis- and tetra-iridoids. So far, analgesic and anti-inflammatory properties of Pterocephalus hookei, connected with the presence of triterpene saponins, have been proven, along with analgesic and antiarthritic properties of Dipsacus asperoides, probably determined by the presence of asperosaponin VI. Also, neuroprotective properties related with the activity of saponin fractions in the extract of Dipsacus asperoides have been demonstrated, just as cardioprotective properties of asperosaponin X and VI from D. asperoides. The polysaccharide isolated from the roots of Dipsacus asperoides showed antioxidant and cytotoxic activity in relation to the cells of osteosarcoma. Antiproliferative activity of gigantoside D and E from Cephalaria gigantea against the cells of melanoma and human leukemia has been determined, as well as antimicrobial properties of Succisa pratensis, Succisella inflexa, Knautia arvensis, Scabiosa ochroleuca, and Dipsacus silvestris.

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