The perspectives of the use of metabolomics measures in viral hepatitis

*Tomasz Kryczka¹, Piotr Małkowski², Dorota Zarębska-Michaluk³, Wiesław Kryczka^{3, 4}

Summary
Metabolomics is one of the ‘-omic’ sciences - beside genomics, transcriptomics and proteomics - belonging to systems biology. It represents an emerging and powerful discipline that provides an explanation of accurate small molecule fingerprints related to the disease. It is an interdisciplinary field of science, which combines analytical chemistry, new technology platforms, mass spectrometry, and NMR spectroscopy with a sophisticated data analysis. In this review we highlight the importance of metabolomics as a potential tool for uncovering metabolic changes in HBV and HCV infections of the liver and for discovering novel biomarkers to improve diagnosis, management and prognosis of the liver diseases.

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