Rak jajnika – pośrednie potwierdzenie postnatalnej obecności pierwotnych komórek płciowych w jajnikach dorosłych kobiet

*Leopold Śliwa

Summary
The establishment of maximum reserve of the oogenetic cells in early fetal life and the lack of possibility of the multiply in postnatal period known and proved in reproductive biology. According to effects of experimental investigation, there are primordial germ cells in the ovarian envelope (tunica albuginea), with are able to undergo the mitotic divisions. Moreover, are postulates that oocyte undergo meiosis and mature in the formed ovarian follicles. This phenomenon was called a neo-oogenesis. The results of the following experimental and clinical research may confirm the neo-oogenesis hypothesis in adult mammals female. There are some evidences in support of germ cells and neo-oogenesis existence in the adult ovary. One of them is the observation of ovarian cancers development, mainly teratoma. The histological structure and course of teratoma disease indicate that this cancer type derives from ovarian germ cells. Nowadays, more precise examinations are needed to explain the model of postnatal oogenesis in mammals.

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