Comment

The past 30 years have brought a major progress in the knowledge and management of liver disease. Epidemiological data concerning the four major causes (alcohol consumption, hepatitis B or C and metabolic syndromes) of liver disease in Europe as well as in Poland are scare.

The numerous aspects of epidemiology, natural course, clinical picture and diagnostics of the chronic liver disease remain unclear. Therapy of them especially in the end stage of liver

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