Liście Serratula quinquefolia M.B. nowym źródłem arbutyny

Monika Morąg¹, *Gerard Nowak¹, Anna Michalak²

Summary
Arbutin – glycosylated hydroquinone, is a natural compound occurring in several species of Ericaceae, Lamiaceae, Saxifragaceae, Rosaceae, Caprifoliaceae. The compound has also been found in the aerial parts of several species of the Serratula (Asteraceae) genus, including S. quinquefolia M.B., a plant grown in the Medicinal and Cosmetic Herbs Garden of Department of Medicinal and Cosmetic Natural Products, Poznań University of Medical Sciences, Poland. The species occurs naturally in wooded areas at the height of 300-1000 m. above sea level, mainly in the region of the Caucasus. It is also common in the meadows of Armenia, Azerbaijan, Greece, Iran and south-west Russia. Our research proves that the aerial parts of Serratula quinquefolia contain constant high concentration of β-arbutin. A measured by HPLC, it is 6.86% according to The European Pharmacopoeia. Such parameters substantiate considering the raw material in question valuable for medicine and cosmetology on account of the well-known antibacterial and whitening properties of arbutin. In the water and methanolic extracts from S. quinquefolia no hydroquinone nor its derivatives (excluding arbutin) have been traced. Our methods of isolation have also shown no occurrence of ecdysones in the aforementioned raw materials.

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