Ekdysony roślinne

*Gerard Nowak, Arletta Moroch, Maria Urbańska, Joanna Nawrot, Lidia Ratajczak, Renata Dawid-Pać

Summary
Ecdysones are present in both animals and plants. These compounds constitute a family of about 300 structures with distinctive physical, chemical and biological properties. They are considered to be of a very polar nature. The plants usually contain one or a few major ecdysteroids along with other closely related compounds occurring in lower amounts. The following phytoecdysones are the most famous: 20-hydroxyecdysone (polypodine A) and polypodine B. The compounds in question, and the materials in which they play a dominant role, are very promising for phytotherapy. Phytoecdysones have been proven to have anabolic activity. They stimulate the protein synthesis in the liver, kidneys and muscles with no apparent detrimental effects to the functions of human organism. Some pharmacological studies indicate a possible increase in human body’s efficiency owing to the influence of phytoecdysteroids. These compounds have been also noted in literature to have a positive effect in hyperglycaemia, hypercholesterolemia and physical and/or mental weakness. There are suggestions of phytoecdysones being applied as a supplement in the treatment of several diseases of the cardiovascular system. However, despite the positive results of pharmacological studies on phytoecdysones and their presence on the pharmaceutical market, the plants containing these compounds are not mentioned in international monographs.

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