The Effects of DAIPING (Diabalance) granule on the Glycolipid Metabolism and PTP1B Expression in Liver of type 2 Diabetes Rats1)
© Borgis - New Medicine 1/2012, s. 21-24
*Ji-An Li1, Shu-Ying Han1, Chun-Yu Tian1, Jin-Xiu Chu1, Xiang-Bo Gou1, Ting Han1, Jing Bai1, Yan-Ping Zhang1, Peng Cui1, Bo-Nan Zhang1, Hai-mei Bo1, Chen Zhen2, Júlia Bartos3
Summary
Aim of the study. The aim of the study is to investigate the effects of the DAIPING (Diabalance) granule on triglyceride (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and the free fatty acids (FFA) in type 2 diabetes rats. At the same time the PTP1B expression in liver of type 2 diabetes rats was evaluated with the use of western blotting and real-time quantitative PCR.
Results. The Daiping particle can decrease the TG, TC, LDL-C and FFA, and can also significantly inhibit the PTP1B expression in liver of type 2 diabetes rats.
Conclusions. The DAIPING (Diabalance) granule can improve the type 2 diabetes.
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