Ocena aktywności antybiotycznej wyciągów roślinnych

*Elżbieta Hołderna-Kędzia, Bogdan Kędzia

Summary
The research study included 387 dried and concentrated extracts of 74 herbal plants. Plant extracts obtained using solvents of different polarity. The antibiotic activity of tested extracts determined by susceptibility to international standard strain of Staphylococcus aureus ATCC 6538 P grown in Antibiotic Medium Broth. The antimicrobial activities of extracts compared with reference substance chloramphenicol for their effectiveness and Minimum Inhibitory Concentration (MIC). The research identified 17 extracts with the highest antibiotic activity (MIC ≤ 0.1 mg/ml). Among the most antimicrobial active extracts are those derived from the thalli Cladonia uncialis by acetone, ethylene ether, heptane, methanol (MIC = 0.0005-0.01 mg/ml) extraction. The ethyl acetate and hexane extracts of the root of Salvia miltiorrhiza showed as well the high antimicrobial activity (MIC = 0.01 mg/ml). To most antibiotic active group include the ethyl ether and paraffin oil extracts (MIC within the range 0.4 i 1.7 mg/ml). The least active group was the water extracts (mean MIC = 15.5 mg/ml). The remaining 9 groups include ethanol, acetone and hexane, exhibit the average MIC values between 2.5-5.0 mg/ml.

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