Działanie substancji olejkowych na bakterie i grzyby

© Borgis - Postępy Fitoterapii 1/2010, s. 3-8

*Elżbieta Hołderna-Kędzia

Summary
The aim the study was to assess the antibiotic activity of the 36 essential oil components of four classes of aromatic organic compounds (monoterpene, sesquiterpenes, phenols, polyacetylene). The antimicrobial activity of these compounds was tested against standard and clinical strains Gram-positive cocci (Staphylococcus aureus), Gram-negative bacilli (Escherichia coli), yeast-like fungi (Candida albicans). The activity was determined by the serial dilutions method in Antibiotic Medium for bacteria, and Sabouraud Liquid Broth for fungi. In our study, the eight of a thirty-six essential oil components: limonene, p-cymene, terpinolene, thymol, carvacrol, borneol, anethole, cinnamic aldehyde, tested against standard strains of bacteria and fungi demonstrated the highest antibiotic activity (MIC = 250-750 ?g/ml). In turn, a four of seventeen essential oil components: tested against clinical strains showed, accordingly, the highest antibiotic activity (MIC = 25-250 ?g/ml). Remained essential oil components demonstrated a very low activity against one, two or three standard or clinical strains (MIC = 300-1000 ?g/ml).

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