Antinuclear antibodies in patients with Lyme disease

© Borgis - New Medicine 4/2010, s. 152-155

*Małgorzata Tokarska-Rodak¹, Justyna Niedźwiadek¹, Hanna Fota-Markowska², Filip Śmiechowicz², Bożena Gajownik³, Roma Modrzewska², Maria Kozioł-Montewka¹

Summary
Aim. The aim of the study was to determine the relation between B. burgdorferi infection in patients with clinical symptoms of Lyme disease and presence of antinuclear antibodies (ANA) depending on the duration of the disease and in the aspect of the erythema migrans (EM) experience.
Material and methods. The study was conducted in a group of 110 patients with the second stage of Lyme disease hospitalized during 2007-2009. The ANA were determined by the IIFT test and the Western blot test.
Results. Positive ANA results (IIFT test) were obtained for 16 patients. The presence of ANA (Western blot test) was confirmed in 4 women who reported a single bite by ticks before 2000, EM presence in the past and the administration of antibiotic treatment due to Lyme disease because of EM and ailments concerning bone-joint structure but without the presence of autoimmune diseases.
Conclusions. The relation between primary diagnosis of Lyme disease in the form of EM and occurrence in the late period is possible despite the application of treatment of joint symptoms with simultaneous presence of ANA antibodies.

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