Działanie probiotyków na organizm człowieka. Cz. II. Zastosowanie probiotyków w leczeniu i profilaktyce chorób

*Anna Kędzia

Summary
Several microorganism strains, mainly those belonging to the genera Lactobacillus, Bifidobacterium, Streptococcus or Saccharomyces are currently used as probiotics. They contains usualy 1-2, seldom more different strains bacteria or yeast in high amounts (≥10⁹ CFU). Important characteristics of probiotics bacteria include their abilities to suppress the proliferation and virulence of pathogenic microorganisms by different mechanisms. Due to the production of diverse antimicrobial factors (eg. bacteriocins, non-peptide compounds, lactic acid) probiotics may be considered for the prevention and treatment of a variety of diseases. Several studies showed the efficacy of administration of probiotic bacteria for prophylactic and therapeutic use against diarrhea newborns, children and elderly, in the therapy of antibiotics-related diarrhea (with Clostridium difficile), traveler´s diarrhea, Helicobacter pylori gastroenteritis, irritable bowel syndrome, ulcerative colitis, Crohn´s disease, urogenital infections, prevent to allergic reactions and atopic disease, and respiratory infection in children. The probiotics eg. lactobacilli and bifidobacteria enhancing of immune system and supporting the physiological function of the host. In addition probiotic bacteria helping lactose intolerant individual digest lactose. Probiotics have been found to inhibit intestinal microorganisms enzymes involved in the synthesis of colonic carcinogens, and reduce the risk of cancer.

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