On the phytochemical investigation of the genus Gentiana used for the treatment of liver diseases in Mongolian Traditional Medicine¹

Dencmaa Dungerdorj, S. Tsetsegmaa, S. Purevsuren, B. Bayasgalan

Summary
On the result of phytochemical investigation of 8 species of the genus Gentiana growing in Mongolia 27 xanthons, 15 flavonoids, 11 secoiridoids, 3 organic acids, totally more than 50 compounds were isolated and identified. From Gentiana barbata 8 xanthons, 2 secoiridoids, 2 flavonoids; from G. macrophylla 1 secoiridoid, 2 flavonoids; from G. decumbens 2 secoiridoids, 4 flavonoids; from G. algida 1 secoiridoid, 3 flavonoids; from G. acuta 6 xanthons, 1 secoiridoid, 3 flavonoids, 1 organic acid; from G. uniflora 2 xanthons, 1 organic acid; from G. azurium 6 xanthons, 3 secoiridoids, 1 flavonoid; from G. pulmonaria 5 xanthons, 1 secoiridoid were isolated. 7-O-β-D-glucopiranosyl-1-hydroxy-3,8-dimethoxyxanthon from Gentiana barbata, 1,3,5-trihydroxy-8-methoxyxanthon from G. azurium, 1-O-β-D-glucopiranosyl-3,5-dihydroxy-8-methoxyxanthon, 1-hydroxy-3-methoxy-5-acetoxy-8-acetyl-O-β-D-fructofurano-sylxanthon from G. pulmonaria were novel compounds found in nature for the first time and their structures were elucidated by spectral analysis.

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