Dieta ketogenna jako terapia w lekoopornej dziecięcej epilepsji

*Małgorzata Kardasz, Danuta Pawłowska

Streszczenie
Fasting and other dietary regimens have been used to treat epilepsy since biblical times. The ketogenic diet mimics the metabolic effects of ketosis, was used by modern physicians to treat intractable epilepsy beginning in the 1920s. From a serendipitous observation that fasting temporarily suppresses epileptic seizures. With the rising popularity of drug treatments however, the ketogenic diet lost its previous status and was used in only a handful of clinics for most of the 20^th century. The diet regained widespread recognition as a viable treatment option beginning in 1992 due to the efforts of parent advocate groups. The ketogenic diet is a high – fat, low – carbohydrate and low – protein diet, which is given to drug – resistant children with epilepsy to improve seizure control. There are two types of ketogenic diet. The classical diet, which limits calories to the minimum required for growth. Fat is given in ratio of 4:1 carbohydrate and protein or 3:1, while 75-90% of daily calories are from fat, the remainder of daily calories is from protein and carbohydrates (7% of calories from protein, 3% of calories from carbohydrate). The medium chain triglyceride (MCT) diet provides 40-60% of calories from MCT, 10% from protein, 19% from carbohydrate and 11-31% from other dietary fats. The ketogenic diet has significant potential as a powerful tool for fighting epilepsy. The efficacy of these diet until recently has not been rigorously examined through scientific trials.

To jest tylko fragment artykułu. Aby przeczytać całość, przejdź do Czytelni medycznej.