Nefropatia IgA

*Małgorzata Mizerska-Wasiak

Streszczenie
IgA nephropathy (IgAN) is the most common type of glomerulonephritis worldwide. It is currently viewed as various clinical manifestations of renal lesions such as: gross/microscopic hematuria, proteinuria, nephrotic/nephritic syndrome or acute renal failure. IgA nephropathy has been reported in the past as a benign renal disease. Today we know that it may progress to chronic renal failure. Nephropathy in patients with IgAN progress already in childhood, leading to chronic renal failure in 5-30% of cases within 10 years and 25-50% of cases within 20 years. Complete remission has been reported in 3-30% patients with IgAN. The variants of initial manifestation and long-term follow up makes it difficult to asses the risk of progression of nephropathy and development of CRF in an individual patient. The treatment of IgAN is currently remains unstandardized among various centers worldwide.
The publication contains new data relative prevalence, pathogenesis, clinical features, risk factor of progression and treatment of IgA nephropathy in children.

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