Szczepienia przeciw zakażeniom wywoływanym przez Haemophilus influenzae typu b

© Borgis - Nowa Pediatria 2/2001, s. 3-5

Marta Wysocka

Streszczenie
This article reviewed actual studies of safety and immunogenity of combination vaccines. Connjugate vaccines are urgently needed to reduce the number of injections given to young children. Infants given combined vaccines experienced a significantly lower antibody response to PRP-T component then infants given PRP-T vaccine as a separate injection. Although anti-PRP geometric mean antibody concentrations and the precent of subjects achieving the 1 microg/ml seroprotective level were lower after mixed administration, they were in the range seen with monovalent Hib vaccines.

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