Morfina i inne opioidy w leczeniu bólu nowotworowego. Czym należy kierować się przy wyborze leczenia u pacjentów z bólem trudnym do uśmierzenia

© Borgis - Nowa Medycyna 6/2002

Aleksandra Kotlińska-Lemieszek, Jacek Łuczak, Ewa Bączyk, Maciej Bączyk

Streszczenie
The past 16 years have proved that the WHO principles are a very effective method of cancer pain management. In about 10-15% of patients, however, the pain control is unsatisfactory which might be due to poor response to the analgesics or side effects that limit further dose escalation.
In the article the authors analyse the known patient and opioid factors determining the so-called „responsiveness”. They focus on the methods of improving the effect of pharmacological treatment, such as adequate adjuvant and breakthrough pain management, parenteral treatment, opioid rotation and simultaneous use of two opioids.

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