Gruźlica lekooporna w Polsce
© Borgis - Nowa Medycyna 1/2009, s. 50-55
*Ewa Augustynowicz-Kopeć, Zofia Zwolska
Streszczenie
Drug-resistant tuberculosis, and particularly multidrug-resistant tuberculosis (MDR-TB is an increasing health problem and a serious challenge to TB control programmes. Information concerning susceptibility patterns of Mycobacterium tuberculosis isolates to tuberculosis drugs is an important aspect of tuberculosis control and surveillance. Analysis of local rates of TB drug resistance is helpful in the detection and monitoring of the predominance of MDR strains, indicating the quality of TB control in a country. Knowledge of the prevalence of primary drug resistance guides the selection of drugs used in initial treatment of tuberculosis. It is believed that acquired resistance is closely related to the efficacy of the treatment programme, and early diagnosis of MDR is essential to prevent its transmission in the community. Patients infected with MDR strains are not only difficult to cure but also more likely to remain sources of infection longer than those with drug-susceptible organisms.
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