EXAMINATION OF THE ULTRASTRUCTURE OF THE RESPIRATORY EPITHELIUM CILIA IN CHILDREN WITH RECURRENT INFECTION OF THE RESPIRATORY TRACT

*Małgorzata Dębska¹, Joanna Peradzyńska², Mieczysław Chmielik¹, Marek Kulus²

Summary
Introduction: The article presents the comprehensive diagnostics of recurrent infections of the respiratory tract in children. The indications for examination of the ultrastructure of the cilia in the respiratory epithelium were analysed.
Aim: To analyse the clinical value of selected diagnostic methods used for recurrent respiratory tract infections.
Material and methods: Patients with recurrent respiratory tract infections hospitalized in the Clinic of Pulmonology and Allergology and the Clinic of Paediatric Laryngology in 2006 and 2007. All the patients underwent basic tests, several of CT of the sinuses, spirometry and bacteriological examination.
Results: In all patients (except one) the results of the basic exams as well as of the chloride levels of sweat were correct. The results of the chest radiography were positive in 18 cases. In all patients the respiratory epithelium was sampled for examination of the cilium ultrastructure. It was sampled from the nose in 27 cases and from the trachea in 4 cases. The most common pathology in the cilium ultrastructure was missing dynein arms.
Conclusions: In almost 100% of cases of children with recurrent infections of the respiratory tract, no cilia or very few of them were present in the respiratory epithelium. Sampling of the respiratory epithelium is a valuable diagnostic method in children with recurrent infection of the respiratory tract.

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