Wczesna interwencja w mukowiscydozie u niemowląt

Aleksandra Światły

Streszczenie
Recent reports suggest that lung involvement develops in cystic fibrosis early in infancy even before the appearance of the first clinical symptoms of lung lesions. This calls for early beginning of treatment for improving mucociliary clearance and lung function, and for prevention or slowing down of irreparable destruction of pulmonary tissue. DNA derived from neutrophils has been demonstrated to be the main factors determining the physicochemical properties of bronchial secretion in this disease. Recombined human deoxyribonuclease (rh-DNase) is regarded as an effective mucolytic agent improving lung function in cystic fibrosis and raising the wellbeing of the patient.

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