Wskazania do leczenia immunosupresyjnego w dermatologii

Julia Warmińska, Anna Kowal, Dorota Krasowska

Streszczenie
Summary
Immunosuppression consists in breaking of different immune reactions. According to mechanism of activity, these drugs reveal effects on each stage of the immune process. Among immunosuppressive drugs steroids, antimetabolites, alkylating agents, cyclosporine, mycophenolate mofetil are used in dermatology. Therapeutic potencial of these drugs is limited by dangerous side effects. Apart from inhibition the excessive immunological response to antigens and because of the lack of specific action, they result in total suppression of the immune system. That in turn produces higher number of infections, the abnormal course of diseases and increased risk of lymphomas and cancers. Therefore the decision on applying any of these immunosuppressive drugs ought to be preceded by thorough analysis of clinical history, indications and contraindications refering to each drugs and potencial toxicity and side effects.

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